Our latest paper in collaboration with the Ronning Lab has been accepted in Organic and Biomolecular Chemistry. The work is titled 'Zwitterionic pyrrolidine-phosphonates: Inhibitors of the glycoside hydrolase-like phosphorylase Streptomyces coelicolor GlgEI-V279S" and the abstract is available here.
Ms. Miranda Dermanelian's summer research project approved
Ms. Miranda Dermanelian, an undergraduate, had her summer research project approved for funding. Congrats Miranda!
Sandeep Thanna Presents at the San Francisco ACS meeting
Sandeep Thanna presented his work on the Synthesis and evaluation of antitubercular agents 2-aminothiophenes and benzo-1,2-selenazol-3(2H)-ones at the Spring ACS meeting in San Francisco. click here for poster
New Paper Published on the synthesis of 2-alkyl-1,2-benzisoselenazol-3(2H)-ones and evaluation against Mycobacterium tuberculosis
New paper published on: Thermal and photoinduced copper-promoted C-Se bond formation: Synthesis of 2-alkyl-1,2-benzisoselenazol-3(2H)-ones and evaluation against Mycobacterium tuberculosis
J. Org. Chem., Just Accepted DOI: 10.1021/acs.joc.7b00440
http://pubs.acs.org/doi/abs/10.1021/acs.joc.7b00440
New paper published on: Exploring Covalent Allosteric Inhibition of Antigen 85C from Mycobacterium tuberculosis by Ebselen Derivatives
New paper published from our collaborators: Exploring Covalent Allosteric Inhibition of Antigen 85C from Mycobacterium tuberculosis by Ebselen Derivatives
ACS Infect. Dis., Just Accepted DOI: 10.1021/acsinfecdis.7b00003
http://pubs.acs.org/doi/abs/10.1021/acsinfecdis.7b00003
New patent issued on polyesters made from renewable feedstock
Title: AMORPHOUS POLYESTER FROM BIO-BASED BIS-FURAN ASSEMBLY
Inventors: Sucheck, Gaitonde, Coleman. U.S. Pat. No. 9,527,952 B1 issued December 27, 2016
The work is related to our paper found here.
Ph.D. candidate Alexander Landgraf joins lab
We are pleased to welcome first year student Alexander Landgraf to the lab. Other events from the fall semester include group multiple presentations at the 12th Midwest Carbohydrate and Glycobiology Symposium and a presentation at the 4th Asian Chemical Biology Conference.
Book Review: Domino and Intramolecular Rearrangement Reactions as Advanced Synthetic Methods in Glycosciences
Our first book review has been published.
Undergratuate Ms. Miranda Dermanelian joins the lab!
B.S. Chemistry Major Ms. Miranda Dermanelian started undergraduate research in the lab today. The first reaction is set up and running :)
New work published on anti-tubercular thiophenes
Our paper titled' Synthesis and evaluation of new 2-aminothiophenes against Mycobacterium tuberculosis" was published in Organic and Biomolecular Chemistry. The best compounds showed potency (MIC = 0.20–0.44 μM) against Mtb strains resistant to isoniazid, rifampicin and fluoroquinolones. A link to the article can be found here.